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Jai Ganesh

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Pheniramine

Pheniramine

Gist

Pheniramine is an antihistamine used to treat allergic rhinitis and pruritus. Naphcon A, Opcon-A, Visine-A. Generic Name Pheniramine DrugBank Accession Number DB01620 Background. Pheniramine is a first-generation antihistamine in the alkylamine class, similar to brompheniramine and chlorpheniramine.

Pheniramine is an 'anti-allergy' medication which contains 'Pheniramine' primarily used to treat allergic conditions. It helps treat allergy-like runny nose, sneezing, congestion, itching, and watery eyes. It is also used to avoid or relieve motion sickness, nasal congestion, and allergic skin irritation.

Summary

Pheniramine is an antihistamine medication used to treat allergic conditions such as hay fever and hives. It works by blocking the effects of histamine, a chemical produced by the body in response to allergens.

What is pheniramine?

Pheniramine is an antihistamine medication that is used to treat symptoms of allergies, such as itching, sneezing, and runny nose.

How does pheniramine work?

Pheniramine blocks the effects of histamine, a chemical released by the body in response to allergens, which helps to reduce allergy symptoms.

What are some side effects of pheniramine?

Common side effects of pheniramine include drowsiness, dry mouth, and blurred vision. Rare but serious side effects can include seizures and irregular heartbeat.

Can pheniramine be used to treat all types of allergies?

Pheniramine is most effective in treating allergies caused by histamine, such as hay fever and allergic rhinitis. It may be less effective in treating allergies caused by other substances, such as food or insect stings.

Is pheniramine safe for everyone to use?

Pheniramine may not be safe for everyone to use, particularly people with certain medical conditions or those taking certain medications. It is important to talk to a doctor before taking pheniramine to ensure that it is safe and appropriate for you.

What are the recommended doses of pheniramine for allergies?

The recommended doses of pheniramine for allergies vary depending on age, weight, and medical history. It is important to follow the instructions on the label or as directed by a healthcare professional.

Is pheniramine available over-the-counter or by prescription only?

Pheniramine is generally available over-the-counter.

Are there any foods or medications that should be avoided while taking pheniramine?

Pheniramine can interact with certain foods and medications, including alcohol and sedatives. It is important to talk to a doctor or pharmacist about any potential interactions before taking pheniramine.

What are some alternative treatments for allergies if pheniramine is not effective or not suitable for a person?

There are several alternative treatments for allergies, including other antihistamines, nasal corticosteroids, and immunotherapy. A healthcare professional can recommend the best treatment options based on an individual's specific needs and medical history.

Details

Pheniramine (trade name Avil among others) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria. It has relatively strong sedative effects, and may sometimes be used off-label as an over-the-counter sleeping pill in a similar manner to other sedating antihistamines such as diphenhydramine. Pheniramine is also commonly found in eyedrops used for the treatment of allergic conjunctivitis.

It was patented in 1948. Pheniramine is generally sold in combination with other medications, rather than as a stand-alone drug, although some formulations are available containing pheniramine by itself.

Side effects

Pheniramine may cause drowsiness or Tachycardia, and over-dosage may lead to sleep disorders.

Overdose may lead to seizures, especially in combination with alcohol.

People combining with cortisol in the long term should avoid pheniramine as it may decrease levels of adrenaline (epinephrine) which may lead to loss of consciousness.

Pheniramine is a deliriant (hallucinogen) in toxic doses. Recreational use of Coricidin for the dissociative (hallucinogenic) effect of its dextromethorphan is hazardous because it also contains chlorpheniramine.

Chemical relatives

Halogenation of pheniramine increases its potency 20-fold. Halogenated derivatives of pheniramine include chlorphenamine, brompheniramine, dexchlorpheniramine, dexbrompheniramine, and zimelidine. Two other halogenated derivatives, fluorpheniramine and iodopheniramine, are currently in use for research on combination therapies for malaria and some cancers.

Other analogs include diphenhydramine, and doxylamine.

Stereoisomerism

Pheniramine contains a stereocenter and can exists as either of two enantiomers. The pharmaceutical drug is a racemate, an equal mixture of the (R)- and (S)-forms.

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